The NITAG recommends starting with conjugate vaccines (PCV13) and then administer PPSV23 in those over 65 years of age. If PPSV23 is administered first, the placement of PCV13 should be generated 1 year later, not shortening the time. Immunologically, due to the vaccinal response of PPSV23, this interval of at least 1 year is recommended; If there are immunocompromising conditions, cochlear implants, or CSF fistulas, the vaccine can be administered as early as 8 weeks; The recommendation is the same for persons with chronic conditions under 65 years of age.