The country must continue making efforts to complete the basic schedule plus a booster dose; Based on current national and international scientific and epidemiological evidence, a second booster dose is established 4 months after the application of the initial booster starting on Monday, April 4 for Health Workers, other groups (older 12 years of age, immunocompromised, rescue teams, population aged 60 and over); Manage characterization of the vaccination status of patients hospitalized for COVID-19 in its severe form; The second booster dose will be with the Pfizer vaccine; Improve the offer of vaccination services for the sustained vaccination scheme.